United States Department of Agriculture patents. 1998 Dec. 15, no. 5,849,299, 8 p.
NALT Subjects:
Gallid herpesvirus 2 virus replication Marek disease disease control live vaccines patents USDA United States
Issue Date:
15-Dec-1998
Abstract:
A Marek's disease vaccine comprising an attenuated revertant virus derived as a clone of Md11/75/R2 or an antigenic component of the virus is characterized by a markedly reduced pathogenicity compared to the parent virus, without a comparable loss in immunogenicity. Attenuated revertants of the invention are exemplified by Md11/75/R2/23 and Md11/75/R2/29. These viruses or immunogenic components thereof can be formulated into monovalent and polyvalent vaccines.
